Reverin LA 230

FOR ANIMAL USE ONLY

REVERIN LA 230
Long-acting injectable solution
Reg. No. G3521 (Act 36/1947)

INDICATIONS
Reverin LA 230 is indicated for the treatment and control of conditions caused by, or associated with oxytetracycline susceptible organisms. Its long action is recommended for veterinary, practical or economic reasons if it is not possible or desirable to handle and treat the animal more frequently.
Cattle
For the treatment of tick-borne gallsickness (anaplasmosis), heartwater, footrot, pneumonia, navel-ill and joint-ill.
Sheep and Goats
For the treatment of heartwater, pneumonia, joint-ill, footrot and navel-ill.
Pigs
For the treatment of pneumonia, footrot, joint-ill and navel-ill.

COMPOSITION
Each mℓ contains 230 mg oxytetracycline hydrochloride (23 % m/v).

CONTENTS
A clear, sterile, stable and ready-to-use injection which provides sustained blood levels for 3 to 5 days following one intramuscular injection of 1 mℓ/10 kg body mass.

STORAGE
Store in a cool dark place (at or below 30 °C.)
As with other oxytetracycline solutions, darkening may occur during use; this does not reduce the potency of the product.

WARNINGS

• Withdrawal period: Do not slaughter animals for human consumption within 28 days of last treatment. Do not use milk for human consumption within 5 days of last treatment.
• Use Reverin LA 230 only in cattle, sheep, goats and pigs.
• DO NOT ADMINISTER Reverin LA 230 TO PIGLETS ON THE SAME DAY THAT THEY ARE INJECTED WITH IRON.
• Dispose of empty containers according to local waste disposal regulations and do not reuse for any other purpose.
• KEEP OUT OF REACH OF CHILDREN, UNINFORMED PERSONS AND ANIMALS.
• Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

DIRECTIONS FOR USE – USE ONLY AS DIRECTED
DOSAGE

• Reverin LA 230 is designed for single intramuscular injection at 1 mℓ/10 kg body mass which gives a dosage of 23 mg oxytetracycline hydrochloride per kg live mass.
• If the product is used intravenously, no long acting effect will be achieved.
• Normally one injection is sufficient to treat diseases mentioned above.
• A second injection at 72 hours (3 days) after the initial injection may be given if necessary. Treatment should always be continued until total recovery.
• For adult animals it is recommended that the dose be split and given at two injection sites.
  • Cattle – not more than 20 mℓ per site.
  • Pigs – not more than 10 mℓ per site.
  • Sheep and goats – not more than 5 mℓ per site.
• For pigs under 10 kg it is preferable to inject subcutaneously. This route is not preferred for other animals as it may cause some swelling.

Administration
Injection in the neck is preferable to the rump, as this tends to give higher antibiotic blood levels and causes less tissue damage.
Inject deep into the fleshy part of the muscle. Temporary discomfort may be caused by i.m. injections; massaging the site of injection will reduce discomfort and will help to disperse the antibiotic at the site of injection.

N.B. For rapid recovery a prompt and accurate diagnosis is essential. It is, therefore, always advisable to consult your veterinarian for a correct diagnosis.

SIDE EFFECTS AND SPECIAL PRECAUTIONS

• Hypersensitivity reactions are known to occur with the use of certain classes of antibiotics. These reactions can range from mild, transient skin reactions to fatal anaphylactoid shock. If administered to an animal that is hypersensitive, anaphylactic shock may occur.
• Adrenaline, corticosteroids and antihistamines should be administered to treat anaphylaxis.
• If known hypersensitivity exists in an individual or group of animals, this product should be used with caution and only after consulting with a veterinarian.
• Use of injectable medicinal preparations may result in localised tissue reactions and temporary swelling at the injection site. Treatment is symptomatic and supportive.
• Natural bacterial resistance may develop to antibiotic preparations. If this is suspected please consult with your veterinarian.

PRESENTATION
20 mℓ; 25 mℓ and 40 mℓ: A ready-to-use polyethylene syringe in a carton.
100 mℓ: Amber multi-dose glass vial closed with chlorobutyl stopper and aluminium cap in a carton.
100 mℓ; 500 mℓ and 1 ℓ: Polyethylene vial closed with chlorobutyl stopper and plunger with Alu-cap in a carton.
Not all the pack sizes may be marketed.

REGISTRATION HOLDER
Intervet South Africa (Pty) Ltd.
20 Spartan Road, Spartan
1619, RSA
Tel: +27 (0) 11 923 9300
Fax: +27 (0) 11 392 3158
ww.msd-animal-health.co.za

DATE OF PUBLICATION OF THIS PACKAGE INSERT
28 November 2019